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Tae Hwan Kwak Selected Research

dunnione

12/2018Pharmacological stimulation of NQO1 decreases NADPH levels and ameliorates acute pancreatitis in mice.
3/2016Dunnione ameliorates cisplatin ototoxicity through modulation of NAD(+) metabolism.
9/2015A Dunnione Compound MB12662 Improves Cisplatin-Induced Tissue Injury and Emesis.
9/2013Inhibitory effects of a β-dunnione compound MB12662 on gastric secretion and ulcers.

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Tae Hwan Kwak Research Topics

Disease

7Neoplasms (Cancer)
11/2018 - 01/2013
5Ototoxicity
03/2016 - 03/2014
4Obesity
01/2018 - 04/2009
3Heart Failure
01/2019 - 01/2014
3Mitochondrial Diseases (Mitochondrial Disease)
01/2016 - 03/2014
2Pancreatitis
12/2018 - 01/2017
2Inflammation (Inflammations)
12/2018 - 01/2016
2Body Weight (Weight, Body)
09/2015 - 07/2012
2Hypertension (High Blood Pressure)
02/2014 - 08/2011
2Fatty Liver
02/2014 - 07/2012
1Neural Tube Defects (Exencephaly)
01/2022
1Parkinson Disease (Parkinson's Disease)
01/2020
1Cardiotoxicity
11/2018
1Cardiomegaly (Heart Hypertrophy)
01/2018
1Stroke (Strokes)
01/2017
1Ischemic Stroke
01/2017
1Disease Progression
01/2016
1Peripheral Nervous System Diseases (PNS Diseases)
01/2016
1Fibrosis (Cirrhosis)
01/2016
1Vomiting
09/2015
1Atrophy
09/2015
1MELAS Syndrome (Syndrome, MELAS)
11/2014
1Lactic Acidosis
11/2014
1Hearing Loss (Hearing Impairment)
04/2014
1Acute Kidney Injury (Acute Renal Failure)
03/2014
1Alcoholic Fatty Liver
02/2014
1Liver Diseases (Liver Disease)
02/2014
1Cardiomyopathies (Cardiomyopathy)
01/2014
1Ulcer
09/2013
1Huntington Disease (Huntington's Disease)
01/2013
1Neuroblastoma
01/2013
1Hyperlipidemias (Hyperlipidemia)
07/2012
1Vascular System Injuries
04/2009
1Atherosclerosis
04/2009
1Metabolic Syndrome (Dysmetabolic Syndrome X)
04/2009

Drug/Important Bio-Agent (IBA)

11NAD (NADH)IBA
11/2018 - 04/2009
6Cisplatin (Platino)FDA LinkGeneric
03/2016 - 03/2014
6beta-lapachoneIBA
11/2014 - 04/2009
5Sirtuin 1IBA
01/2019 - 01/2013
4dunnioneIBA
12/2018 - 09/2013
4Proteins (Proteins, Gene)FDA Link
11/2018 - 01/2013
4quinone (benzoquinone)IBA
11/2014 - 04/2009
3LipidsIBA
01/2018 - 07/2012
3Therapeutic UsesIBA
01/2017 - 04/2009
3Oxidoreductases (Dehydrogenase)IBA
02/2014 - 04/2009
2Reactive Oxygen Species (Oxygen Radicals)IBA
12/2018 - 01/2016
2DNA AdductsIBA
01/2016 - 03/2014
2Pharmaceutical PreparationsIBA
11/2015 - 08/2011
2Triglycerides (Triacylglycerol)IBA
01/2014 - 07/2012
1Anticonvulsants (Antiepileptic Drugs)IBA
01/2022
11- Methyl- 4- phenyl- 1,2,3,6- tetrahydropyridine (MPTP)IBA
01/2020
1NeurotoxinsIBA
01/2020
1Lysine (L-Lysine)FDA Link
01/2019
1Sarcoplasmic Reticulum Calcium-Transporting ATPasesIBA
01/2019
1EnzymesIBA
12/2018
1CeruletideIBA
12/2018
1NADPH Oxidases (NAD(P)H oxidase)IBA
12/2018
1NADP (NADPH)IBA
12/2018
1Biomarkers (Surrogate Marker)IBA
11/2018
1Messenger RNA (mRNA)IBA
11/2018
1Doxorubicin (Adriamycin)FDA LinkGeneric
11/2018
1salicylhydroxamic acid (SHAM)IBA
01/2017
1InflammasomesIBA
01/2017
1Poly (ADP-Ribose) Polymerase-1IBA
03/2016
1Glucose (Dextrose)FDA LinkGeneric
11/2014
1coenzyme Q10 (CoQ10)IBA
11/2014
1idebenoneIBA
11/2014
1Nitric Oxide Synthase Type III (Endothelial Nitric Oxide Synthase)IBA
02/2014
1Histone Deacetylases (Histone Deacetylase)IBA
02/2014
1GuanosineIBA
02/2014
1Phosphotransferases (Kinase)IBA
02/2014
1Fatty Acids (Saturated Fatty Acids)IBA
02/2014
1Protein Kinases (Protein Kinase)IBA
02/2014
1Adenosine (Adenocard)FDA LinkGeneric
02/2014
1Acyl Coenzyme A (Acyl CoA)IBA
01/2014
1Ethanol (Ethyl Alcohol)IBA
09/2013
1Pantoprazole (Protonix)FDA LinkGeneric
09/2013
1Proton Pump InhibitorsIBA
09/2013
1polyglutamineIBA
01/2013
1glabridinIBA
07/2012
1CholesterolIBA
07/2012
1AMP-Activated Protein KinasesIBA
07/2012
1Antineoplastic Agents (Antineoplastics)IBA
04/2009
1PyransIBA
04/2009
1Niacinamide (Nicotinamide)FDA LinkGeneric
04/2009
1AdenineFDA LinkGeneric
04/2009

Therapy/Procedure

4Drug Therapy (Chemotherapy)
11/2018 - 08/2015
3Therapeutics
01/2017 - 04/2009
1Transplantation
01/2017
1Oral Administration
01/2014